Nowadays,  due to hectic modern lifestyle, more and more women lead, the decision  of marriage and starting a family in the reproductive age, has caused the increase of age-related infertility cases.

It has been scientifically proven, that with the age quantity and quality of oocytes decrease and the occurrence of chromosomal aberrations raises considerably. This means there are less and less chances that after fertilization the oocyte will have enough potential to become a healthy embryo and the risk of chromosome abnormalities, inborn deformities and miscarriages increases.

To prevent and stop oocyte ageing, oocyte vitrification, a cutting-edge ART procedure has been successfully used worldwide. The invention of oocytes vitrification made possible the significant improvement of the oocyte ability to survive the warming process, thus increases chances for pregnancy establishment, as due to rapid replacement of the water, contained by an oocyte with an antifreezing agent by which the formation of ice crystals which could lead to the egg destruction is prevented.

During vitrification oocytes are put in liquid nitrogen at a temperature of  –196 °C and are frozen instantly. Once the oocytes are vitrified, they can be stored for many years in special cryogenic tanks at IVF units without any thread to their quality. 

The procedures of hormonal ovarian stimulation with further oocyte retrieval precede the oocyte cryopreservation. After a thorough evaluation of all harvested oocytes, performed in the laboratory by the embryologist, only mature and high quality oocytes are selected for vitrification and will be cryopreserved until the patient’s IVF treatment cycle will be planned and scheduled.

Freezing eggs is also used for a number of diseases, such as systemic lupus erythematosus, renal disease, or sickle cell disease and some medical conditions: endometriosis, large or recurring ovarian cysts, premature ovarian failure that jeopardize a woman’s fecundity. Egg freezing process is also recommended to oncologic patients before chemo- or radio therapy.

The majority of IVF units encourage women to consider the option of their egg freezing in their late 20s to early 30s if they do not have a reproductive partner or do not plan to start the family.

The potential chances of the future pregnancy from the vitrified oocytes greatly depend on the age a woman takes the decision to undergo the social freezing program and the number of frozen oocytes and the average number.

Patient age at oocyte retrieval   

Expected number of eggs to be frozen

<34

12

35-37

12-15

37-39

15-20

40+

 

20+